Landscape reveals critical network structures for sharpening gene expression boundaries
نویسندگان
چکیده
منابع مشابه
Noise drives sharpening of gene expression boundaries in the zebrafish hindbrain
Morphogens provide positional information for spatial patterns of gene expression during development. However, stochastic effects such as local fluctuations in morphogen concentration and noise in signal transduction make it difficult for cells to respond to their positions accurately enough to generate sharp boundaries between gene expression domains. During development of rhombomeres in the z...
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ژورنال
عنوان ژورنال: BMC Systems Biology
سال: 2018
ISSN: 1752-0509
DOI: 10.1186/s12918-018-0595-5